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Prevalence and diversity among temperate bacteriophages (prophages) in the genome of methicillin-resistent staphylococcus aureus (MRSA) isolates from the food-chain
Project
Project code: BfR-BIOS-08-1322-440
Contract period: 01.04.2010
- 31.12.2010
Purpose of research: Applied research
The presence of temperent phages (prophages) in Staphylococcus aureus clonal lineages greatly influences the pathogenic potential of strains by encoding of virulence factors (such as Panton-Valentin-Leukocidin, enterotoxin A). Among methicillin-resistant Staphylococcus aureus (MRSA) strains isolated in the food chain those, who were assigned to clonal com-plex (CC) 398 do only harbour few virulence factors, particularly in comparison with human-associated Non-CC 398 stains. These findings may be due to a low prevalence of pro-phages in these clonal lineages. Hence, selected families of prophages may have the pos-sibility to integrate into the genome of these CC398 MRSA strains, only. However, investiga-tions into the prevalence and diversity of prophages in CC398 are lacking up to present.
Section overview
Subjects
- Food microbiology
- Toxicology