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Oral 28-day toxicity test in rats using the benchmark dose approach (adapted from OECD TG 407) (EuroMix)
Project
Project code: BfR-LMS-08-1329-571
Contract period: 01.11.2017
- 01.04.2018
Purpose of research: Applied research
Within the framework of the EuroMix project, a 28-day oral toxicity test with three pesticides (in pure form or in binary / ternary mixture) is carried out for the client in female rats. After 28 days, the animals are killed and various organs (liver, kidney, lung, spleen, thymus and brain) are prepared for this final date. These organs / samples are sent to the client and used by the latter for transcriptome analyzes and lipid determinations. In the ITEM, the target organ liver is examined histopathologically.
Section overview
Subjects
- Food Chemistry
- Toxicology
Collaborative Project
EuroMix - A tiered strategy for risk assessment of mixtures of multiple chemicals
