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Application of infrared (IR) and Raman spectroscopy for identification and localization of various bioactive substances in various medicinal and aromatic plants
Project
Project code: JKI-ÖPV-08-1368
Contract period: 01.03.2017
- 31.12.2018
Purpose of research: Applied research
Medicinal and aromatic plants (MAP) have been essential resources for human health from ancient times to the present day. Knowledge of the chemical composition of the secreted substances along with detailed descriptions of the anatomy of these structures may contribute to an enhanced understanding of the role and function of the secreted product. The understanding of occurrence, synthesis, localization, variability and biological activity of plant secondary metabolites requires a multidisciplinary approach whose results might lead to formulation of new herbal remedies able to replace standard synthetic medicaments. Chemical and biological characterization of plant active metabolites is a necessary precondition for formulation of phyto-remedies and herbal preparations and estimation and control of drug quality, namely in terms of qualitative and quantitative composition of plant drugs, is imperative for herb producers, processors, traders and exporters, i.e. in the stakeholder of the MAP value chain. Quality control of MAP is usually obtained by chemical analysis (HPLC, LC-MS, LC-NM, GC-MC ...) or by macroscopic or microscopic investigations (pharmacognosy). Both groups of methods have their advantages as well as limitations, so the results of this project are supposed to contribute to the development of fast screening techniques for the evaluation of the drug quality of selected medicinal plants by applying sophisticated Raman and IR microscopy techniques, which enable obtaining chemical images of the samples. We plan to apply the existing methodology (chemical and histochemical techniques) and to correlate obtained data with IR and Raman spectroscopy. Such combination of applied methodologies will bring new value in research of biologically active plant compounds and as a result of these investigations spectral database library of selected MAP will be created. This database could further be used as a tool for fast estimating quality of selected MAP.
Section overview
Subjects
- Horticulture
- Specialised crops
- Biotechnology
Framework programme
Funding programme
Excutive institution
Institute for Ecological Chemistry, Plant Analysis and Stored Products Protection (JKI-ÖPV)