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miRNA – their role as modulators of metabolic effects
Project
Project code: MRI-PBE-08-1010-miRNA
Contract period: 01.09.2019
- 30.09.2022
Purpose of research: Basic research
miRNAs are non-coding small RNA molecules. They modulate gene expression in several tissues through binding to complementary mRNAs. miRNAs are produced in various cell types (e.g. skeletal muscle after physical activity) and secreted into the circulation, which enables them to exert metabolic effects. Moreover, they can be ingested via dietary sources. It is discussed that miRNAs as modulators of metabolic effects can contribute to sustaining human health, e.g. through effects on immune cell functions or glucose metabolism. The objective of the project is to examine the effects of physical activity and diet on miRNA expression in human plasma samples under controlled and standardized conditions to better understand health sustaining effects of physical activity.
Section overview
Subjects
- Physiology of Nutrition
- Food Chemistry
Framework programme
Funding programme
Excutive institution
MRI - Department of Physiology and Biochemistry of Nutrition (MRI-PBE)
