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SUPASALVAC Salmonella-free broilers by live vaccine-induced innate resistance to colonisation and invasion and novel methods to eliminate vaccine and field strains
Project
Project code: 505523
Contract period: 01.02.2004
- 31.07.2007
Budget: 2,440,000 Euro
Purpose of research: Basic research
Salmonella in broiler poultry remains the major source of infection for man and is the least tractable because of the young age at which broilers are slaughtered and their immunological immaturity. In previous project (FAIR 98-4006) we have found that intestinal colonisation of newly hatched chicks with live, attenuated Salmonella vaccine strains results in the development of a rapid and profound resistance to intestinal infection (from a specific microbiological exclusion mechanism) and also to tissue invasion (from an induction of heterophil infiltration into the intestine).
Section overview
Subjects
- Animal health
