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Projects on "2.8 Development of alternative methods to animal testing"

In vitro tests for photogenotoxicity assessment as alternatives to photocarcinogenicity tests in ro-dents (Project part 1).

Project code: BfR-QUER-02-1334-161
Excutive institution: BfR – Department 3: Department Exposure
Contract period: 2002 - 2004

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List of chemicals with missing IC 50-values and/or LD 50-values

Project code: BfR-ZEBET-02-BfR-Quer-02-A-1328
Excutive institution: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments
Contract period: 2004 - 2004

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Prevalidation of human cornea model based on immortalized corneal cell lines as in vitro alternative to the Draize eye test.

Project code: BfR-ZEBET-02-1328-184
Excutive institution: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments
Contract period: 2004 - 2006

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Replacement of fetal calf serum in the embryonic stem cell test (EST) – Standardization of culture conditions for proliferation and differentiation of embryonic stem cells of the mouse

Project code: BfR-ZEBET-02-1322-159
Excutive institution: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments
Contract period: 2004 - 2007

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siRNA technology in mammalian cells as alternative of knock-out mice: Functional investigations of proteins of the Myc-Miz-1-TopBP1-network (translation).

Project code: BfR-ZEBET-02-1328-172
Excutive institution: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments
Contract period: 2003 - 2004

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The isolated perfused bovine udder as an in vitro model for the evaluation of sensibilisation/sensitisation induced by chemicals

Project code: BfR-ZEBET-02-1328-175
Excutive institution: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments
Contract period: 2004 - 2006

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Use of transgenic animals in biomedical research in Germany - survey 2001 to 2003 and perspectives to change research to non-animal test methods

Project code: BfR-ZEBET-02-1328-173
Excutive institution: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments
Contract period: 2003 - 2004

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Validation study for testing of skin penetration using biotechnologically devised human skin equivalents. Phase 2: Validation

Project code: BfR-QUER-02-1334-172
Excutive institution: BfR – Department 3: Department Exposure
Contract period: 2004 - 2006

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