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Implementation and Standardization of Microbiota Analyses
Project
Project code: MRI-PBE-08-1010-mikrobiota-analysen
Contract period: 01.02.2017
- 30.06.2022
Purpose of research: Basic research
The physiological impact of human nutrition is strongly modulated by the microorganisms which are mainly living in our large intestine (gut microbiota). Therefore, it is necessary to understand the interactions between nutrition, physiology and microbiota. To study these interactions many novel methods are used and constantly further developed. The obtained results are highly dependent of the used method. For this reason we work in close interaction with other institutes (MRI-Workgroup “food-associated and intestinal microbiota”) to establish new methods and standard operating procedures (SOP). First aim of this project is the best use of the available technologies and the establishement of high quality standards in all concerned laboratories at the the MRI. A second goal is the identification of the variations of the microbiota within the same person along time and between people of a given population, as a preliminary information to design further studies, in which the microbiota is of main interest.
Noemi Hillebrandt: „Beobachtung der Variabilität des humanen intestinalen Mikrobioms anhand der Veränderung biologischer und technischer Einflussgrößen“, 2019, Bachelorarbeit, Karlsruher Institut für Technologie.
Zarah Janda: „Quantification of the Intestinal Human Microbiome using Spike-In Bacteria”, 2020, Bachelorarbeit, Karlsruher Institut für Technologie.
Section overview
Subjects
- Physiology of Nutrition
Framework programme
Funding programme
Excutive institution
MRI - Department of Physiology and Biochemistry of Nutrition (MRI-PBE)