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FLI - Institute of Molecular Virology and Cell Biology (FLI - IMVZ)
Institution
Section overview
Description
On 1 March 2014 the 'Institute of Molecular Biology' (IMB) of the FLI was renamed: Institute of Molecular Virology and Cell Biology (IMVZ).
Activities
- Research
Parent institution
Friedrich-Loeffler-Institute - Federal Research Institute for Animal Health (FLI)
Coordinated projects
- A system biological approach of genotype-phenotype-dinstinction in the context of farm animal performance, health and welfare in cattle and pig
- Bats as potential transmitters of rabies: investigation on the occurrence of lyssavirus infections in bats
- Biology of Ebolavirus Inclusion Bodies
- Characterization of the role of the host protein NXF1 in the life cycle of ebolaviruses and other negative-sense RNA viruses
- Development of a diagnostic test for detection of trichinella spiralis infection
- Development of a subunit and inactivated whole virus vaccine for immunisation of cats against an influenza H5N1 infection
- Development of viral vector vaccines/marker vaccines
- Dynamics of avian influenza in a changing world. Coordination
- Elucidation of virulence determinants of highly pathogenic non-H5, non-H7 avian influenza viruses
- Epidemiology and control of rabies infections (National and OIE Reference Laboratory (Office International des Epizooties - World Organisation for Animal Health))
- Investigations on the virulence potential of influenza viruses
- Molecular basis for nuclear egress of herpesviruses
- Molecular biology of piscine herpesviruses
- Molecular Determinants of Lyssavirus-Replication
- Role of Nuclear Interactions of Paramyxoviral Matrix Proteins: Cellular ANP32B in Host Manipulation and Virus Replication
- Role of the host proteins NXF1, UAP56, and CAD in the life cycle of ebolaviruses
- Structure-Function Analysis of Herpesvirus Glycoprotein H
- The importance of farm, domestic and wild animals as a source of Ebola virus infection - collaborative project bezween the Friedrich-Loeffler-Institut, the Institut Pasteur de Guinée in Conakry, Guinea, Sierra Leone Agricultural Research Institut and the Njala University in Sierra Leone
- The Role of Apoptosis in the Biology of New World Arenavirus
- Towards rational design of vaccines against African swine fever in East- and Southern Africa: Correlation of viral genome differences with their impact virulence and by analysis of viral and target cell transcription and protein expression.
Involved in research projects
- Elucidating Pathomechanisms of Bacterial Viral Coinfections with New Biomedical Models
- EPIZONE - Network on epizootic disease diagnosis and control
- Evaluating and controlling the risk of African swine fever in the EU (ASFRISK)
- FLUPIG - Pathogenesis and transmission of influenza virus in pigs
- Investigations on the molecular epidemiology in the wild bird population
- Modern molecular diagnostic methods: ultrarapid ad hoc pathotyping and characterisation of AIV complete genomes
- Specific and sensitive marker diagnostics: Development of a DIVA diagnostic
- Specific and sensitive marker diagnostics: Generation of monoclonal antibodies for serological diagnostic
- Supporting the WHO in the activities on bridging the International Health Regulations (IHR) and the PVS
Contact
FLI - Institute of Molecular Virology and Cell Biology
(FLI - IMVZ)
Südufer 10
17493 Greifswald-Insel Riems
Mecklenburg-Vorpommern
Germany
Phone: +49 38351 7-1102
Fax: +49 38351 7-1151
Email: Bettina.Schuetz(@)fli.bund.de