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FLI - Institute for Bacterial Infections and Zoonoses (FLI-IBIZ)
Institution
Section overview
Description
The Institute for Bacterial Infections and Zoonoses carries out research in the fields of etilogy and control of infectious animal diseases. Thus, investigations on pathogenesis, diagnosis and epidemiology of these diseases are also done. An important part of activities is directed towards diseases and their causative agents originating from animals and posing direct or indirect health risks to man. The institute pursues current developments in animal husbandry and control of zoonoses in order to identify risks to animals and man in advance. The spectrum of activities comprises notifiable animal diseases but also other diseases of great economic relevance and zoonoses. Besides farm animals, pet and zoo animals as well as wildlife are subjects of research and service work. The results of these activities will serve the development and optimisation of diagnostic procedures and the design of control strategies. Research projects are focusing on infections caused by Salmonellae, Campylobacter, Brucellae, Clostridia, Francisellae, Burkholderiae, Mycoplasma and selected viral agents. The following topics are: investigations on prevalence, characterisation of transmission routes and mechanisms, aspects of pathogen persistence, elucidation of infection chains and epidemiological relationships using classical and molecular methods, assessing of zoonotic importance, establishing animal infection models and examination of therapeutics using these models. The majority of research projects is done in close collaboration with the Institute for Molecular Pathogenesis. Official tasks include national reference laboratories for brucellosis, contagious equine metritis, anthrax, black leg, bovine genital campylobacteriosis, glanders, bovine salmonellosis, and tick-borne diseases.
Activities
- Research
Parent institution
Friedrich-Loeffler-Institute - Federal Research Institute for Animal Health (FLI)
Coordinated projects
- ANTIcipating the Global Onset of Novel Epidemics
- Brucellosis, Q-Fever and viral hemorrhagic fevers in Egypt
- Collaborative Project: Inactivation of coxiella burnetii by short time heating of milk - subproject 2
- Collaborative project: Novel approach for the development of a heterosubtypic marker vaccine against avian influenza in poultry – Subproject 2
- Comparative testing of diagnostic of botulism in Germany
- D11.11 To identify fitness factors that confer the ability of Yersiniae to highly replicate under harsh host tissue specific conditions e.g. anaerobic/hypoxic condition as a basis for efficient human-to-human transmission
- Detection of Clostridium botulinum and Clostridium botulinum Neurotoxin. Part of the research Project: Role of Clostridium botulinum in chronic disease
- Epidemiology, prophylaxis and control of Salmonella infections in farm animals and other animal species
- Epizootiology of Q-fever of ruminants and wild mammals and differentiating molecular pathogenesis of Coxiella burnetii in humans and animals
- EsRAM: Development of measures for reduction of antibiotic resistant bacteria along the entire poultry production chain. Subproject 6
- Identification. differentiation and genotyping of Francisella tularensis in organ samples of wildlife and arthropods in Germany
- Importance of Clostridium botulinum in chronic incidence of disease - Detection of Clostridium botulinum and Clostridium botulinum neurotoxin
- Improving blackleg diagnostics and National Reference Laboratory for Blackleg
- Influence of climate change on the transmission of vectors (here: Ixodidae) (UFOPLAN research and development project FKZ 3708 49 400)
- Investigation in broiler chicks with diarrhea followed by growth depression (malabsorption syndrome, MAS)
- Investigation of prevalence of thermophilic campylobacter and different animal species incl. epidemiological investigations
- Mechanisms of colonization and adhesion on chicken intestinal epithelial cells by Campylobacter jejuni
- Molecular-epidemiological studies on the antibiotic resistance of bacteria with zoonotic relevance
- Pathogenesis of mycoplasma diseases in cattle
- Prevalence of human brucellosis, Q-fever and rickettsiosis infections in febrile patients and risk factors related to high risk occupational groups in Northern and Nairobi, Kenya
- Producing standardized sample material with Bacillus anthracis, Burkholderia mallei, and Brucella spp. for Raman spectroscopy and reference analysis using microbiological and molecular biology methods
- Salmonella-free broilers by live-vaccine-induced innate resistance to colonisation and invasion and novel methods to eleminate vaccine and field strains
- Securing the food and feed supply chain from potential bio- and agro-terroristic attempts (SiLeBAT)
- The lab-free CBRN detection device for the identification of biological pathogens on nucleic acid and immunological level as lab-on-a-chip system applying multisensor technologies
- Ticks and tick-borne diseases, investigations about biology of ticks and tick-borne diseases using the epidemiological example of Tick-borne-encephalitis-virus-(TBEV) infection
Coordinated collaborative projects
Involved in research projects
Contact
FLI - Institute for Bacterial Infections and Zoonoses
(FLI-IBIZ)
Naumburger Straße 96a
07743 Jena Jena
Mecklenburg-Vorpommern
Germany
Phone: +49 3641 804 200
Fax: +49 3641 804 228
Email: Heinrich.Neubauer(@)fli.bund.de