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Biochemical Institute for Environmental Carcinogens (Prof. Dr. Gernot Grimmer-Foundation) (BIU)
Institution
Section overview
Description
The causes for many human diseases and the disturbance of the biological balance in nature and the environment have been insufficiently studied so far. For various reasons public enterprices cannot support these studies to an extent required. Hence, urgent scientific work cannot be started and essential consequences for the human and environmental benefit cannot be drawn. Only a personal engagement and support of research by private and industrial resources may meet this inconvenience. Your financial support could be an important contribution to overcome these problems. The Biochemical Institute for Environmental Carcinogens is involved in research on causes of cancer formation by environmental hazards and on the reduction of human and animal health risk.
Activities
- Research
Involved in research projects
- Dietary exposures to polycyclic aromatic hydrocarbons and DNA damage
- Effects of natural occuring fatty acids on the bioavailability and the metabolism of polycyclic aromatic hydrocarbons by taking the example of benzo[a]pyrene
- Fatty acids as endocrine disruptors: Influence of chain length, branched chains and multiple bonds of fatty acids on the activity of the estrogen receptors ER-Alpha and ER-Beta
- Interaction between metabolism and transport of toxicological-relevant substances in the gastrointestinal barrier
- Investigation of biomarkers of water pipe smoke
- Molecular characterization of toxicological properties of the marine biotoxin okadaic acid in in vitro models for the human intestinal barrier and liver
- Molecular mechanisms of the toxicity of perfluorohexanoic acid (PFHxA)
- Molecular mode of action of a long-term exposure to hepatotoxisch pyrrolizidine alkaloids
- Phthalates and their metabolites as endocrine disruptors: Effects of various urine metabolites on the activity of estrogen receptors ERalpha and ERbeta
- Study of mutagenic breakdown products of 1-methoxyindole-3-methyl-glucosinolate on induction of preneoplasias and neoplasia-associated changes in gene expression in a mouse model
Contact
Biochemical Institute for Environmental Carcinogens (Prof. Dr. Gernot Grimmer-Foundation)
(BIU)
Lurup 4
D-22927 Großhansdorf
Schleswig-Holstein
Germany
Phone: 04102-62155
Email: sekretariat(@)biu-grimmer.de