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Studies on the allergenic potential ingredients of commedities and cosmetics using the local lymph node assay
Project
Project code: BfR-PRS-02-G 1330-109
Contract period: 01.01.2004
- 31.12.2005
Purpose of research: Applied research
The allergenic potential of disperse yellow 3 and its metabolite 2-amino-p-cresol shall be investigated using the local lymph node assay. The studies are focussed on dose-response relationship and a possible cross sensitivity. The further aspect of a possible oral sensitization shall be studied using the vulcanizer mercaptobenzthiazol als model substance.; ; In parallel, it is intended to establish a method for measuring skin penetration in vitro.
Section overview
Subjects
- Physiology of Nutrition
- Food Chemistry