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Resource efficient extraction of pharmaceutically active ingredients from steam distillation derived hydrolates and distillation residues (ResiDest)
Project
Project code: JKI-ÖPV-08-1378, 22021517
Contract period: 01.11.2018
- 30.10.2021
Purpose of research: Experimental development
Keywords: renewable ressources, phytopharmaceutical extractionressource efficiency
The aim of the project is the economic and resource-efficient recovery of plant value components. A threestage, cascade-like process concept is to be developed. First, the volatile components are recovered by steam distillation. However, small water-soluble components, e.g. thymol and carvacrol in the so-called hydrolate are then usually discarded. In order to make use of this part as well, a solid-phase cartridge is to be integrated in order to bind the value components of the hydrolates to functionalized silica gel. After completion of the water vapor distillation, the non-water-soluble components of the plant material are extracted by means of conventional solvent extraction or by means of so-called green extraction methods, such as, for example, hot water extraction (PHWE). In parallel, the bound components are eluted from the solid phase cartridge by means of organic solvents such as, for example, ethanol. The influence on the quality and the quantity of the components obtained should also be evaluated by a variation of operating parameters. A subsequent purification of the obtained extracts or essential oils ensures the respectively required product purity in pharmaceutical quality. This process is to be investigated by means of selected sample substances and plants. Through a subsequent physico-chemical modeling of the process, a generally applicable design tool is developed for an integrated extraction of highly pure substances from plants. This is evaluated by means of scaling studies in the industrial environment.
Section overview
Subjects
- Process engineering
- Renewable Resources
Framework programme
Funding programme
Excutive institution
Institute for Ecological Chemistry, Plant Analysis and Stored Products Protection (JKI-ÖPV)