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Collaborative project: A key driver for the emergence and spread of Antibiotic resistance is the use of antibiotics in animal husbandry. Mobile pathogen diagnostics in poultry farming at the point of need should contribute to reducing the use of antibiotics and increasing animal health - subproject E (MEDiaG)
Project
Project code: 281C407E21
Contract period: 01.07.2023
- 30.06.2026
Budget: 60,000 Euro
Purpose of research: Applied research
Keywords: bacteriology, animal welfare, diagnostics, poultry, prevention, animal husbandry, antibiotics, therapy
The aim of the project is to establish mobile on-site diagnostics for the detection and monitoring of multi-resistant pathogens in poultry farming as a basis for deciding on and controlling intervention measures. As part of the project, prevalence monitoring for multi resistant bacteria is being carried out using laboratory diagnostics and a portable sample-to-answer diagnostic system is being researched, which should be available to veterinarians or poultry farmers in the future. By integrating a complex laboratory process into a simple system with just a few manual steps, the analysis can be carried out on site and suitable intervention measures can be initiated immediately. The detection method used allows the diagnostic platform to be miniaturized, creating the basis for a portable and cost-effective device. Without purification of the sample, a sensitive and specific pathogen detection should be carried out in less than 30 minutes. As an alternative to PCR and fluorescence-based detection methods for nucleic acids, isothermal amplification (LAMP) in combination with electrochemical detection makes it possible to dispense with optical analyzers and instrument-intensive thermal cycles and thus achieve a new level of miniaturization with the same or better sensitivity. In order to identify risk factors for multi resistant bacteria, an extensive data set from bacteriological and sequence analyzes as well as operating parameters in the poultry farm is collected. In this way, the multi resistant bacteria status is documented depending on operational changes and a guideline with concrete recommendations for action is derived. The developed multi resistant bacteria monitoring lays the foundation for a future quality classification of products or companies. The resulting market economy incentives can reduce both the prevalence of multi resistant bacteria and the use of antibiotics.
Section overview
Subjects
- Animal health
Framework programme
Funding programme
Excutive institution
Funding institution
Project management agencies
Associated projects: MEDiaG
- Collaborative project: A key driver for the emergence and spread of Antibiotic resistance is the use of antibiotics in animal husbandry. Mobile pathogen diagnostics in poultry farming at the point of need should contribute to reducing the use of antibiotics and increasing animal health - subproject A
- Collaborative project: A key driver for the emergence and spread of Antibiotic resistance is the use of antibiotics in animal husbandry. Mobile pathogen diagnostics in poultry farming at the point of need should contribute to reducing the use of antibiotics and increasing animal health - subproject B
- Collaborative project: A key driver for the emergence and spread of Antibiotic resistance is the use of antibiotics in animal husbandry. Mobile pathogen diagnostics in poultry farming at the point of need should contribute to reducing the use of antibiotics and increasing animal health - subproject C
- Collaborative project: A key driver for the emergence and spread of Antibiotic resistance is the use of antibiotics in animal husbandry. Mobile pathogen diagnostics in poultry farming at the point of need should contribute to reducing the use of antibiotics and increasing animal health - subproject D
