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Mosquito and mosquito-transmitted zoonosis in Germany (continuation) (CuLiFo3)
Project
Project code: 2819107A22
Contract period: 01.01.2023
- 30.06.2026
Budget: 911,629 Euro
Purpose of research: Experimental development
Keywords: zoonosis, epizootic, climate change adaptation, prevention, other aquatic organisms, health-related consumer protection, diagnostics
Five partner institutions (Bernhard Nocht Institute for Tropical Medicine, BNITM; Friedrich Loeffler Institute, FLI; University of Oldenburg, CvO; Leibniz Center for Agricultural Landscape Research, ZALF; Society for the Promotion of Mosquito Control, GFS) and one associated partner (Fraunhofer Institute for Cell therapy and immunology, IZI) will analyze the effects of biotic and abiotic factors on the occurrence of arboviruses of veterinary and human medicine importance in Germany in CuliFo3. The scientific concept builds on findings from the CuliFo and CuliFo2 projects previously funded by the BLE. Results are used to enable timely, targeted responses to manage risk situations and to develop adequate catalogs of measures. For an early warning system, the influence of insect-specific viruses on arbovirus replication in vectors, of co-infections with arboviruses on vector capacity, excretion dynamics and minimal infectious dose of arboviruses for culicides is investigated. Also whether infections of birds with USUV or TBEV lead to cross-protection against WNV. The clinical relevance of arbovirus infections will be assessed via examination of blood donor and patient samples and dead wild birds, and arbovirus surveillance by analysis of culicide and bird virome and validation of the use of FTA maps. Modeling of landscape structures as mosquito habitat, recording of flight activities, physical-chemical and ecological parameters as well as mosquito resting places contribute to a better understanding of vector ecology. The biological control of culicide larvae by copepods and with microbial control agents is evaluated as an environmentally friendly and sustainable strategy. A cost-benefit analysis of the effectiveness and socio-economic consequences of measures to combat arboviruses examines the advantages and disadvantages of the various methods.
Section overview
Subjects
- Animal Husbandry
- Animal health
