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Detection and characterization of noro- and rotaviruses of chicken as potential zoonotic food-borne pathogens
Project
Project code: BfR-BIOS-08-1322-260
Contract period: 01.05.2007
- 31.12.2009
Purpose of research: Basic research
Infections with noro- and rotaviruses are of increasing significance in infectious gastroenteritis of humans. Both pathogens could be transmitted through contaminated food. Animal viruses, which are closely related to human viruses exist in both virus families and zoonotic transmission may be possible. In contrast to the mammalian noro- and rotaviruses, those of the birds are only poorly investigated until now. However, for other viruses (e.g. influenza viruses) or bacteria (e.g. Salmonella) it is well-known that birds have a high significance as reservoirs or starting point for human food-borne infections. Therefore, in this project, samples of chicken, in which noro- or rotavirus particles have been detected by electron microscopy, will by analysed using methods of molecular biology. Parts of the viral genomes will be sequenced and the sequences will be compared with those of human viruses. The results of the investigations should help to estimate the zoonotic potential of noro- and rotaviruses of chicken and their contribution to human food-borne infections.
Section overview
Subjects
- Animal health
- Physiology of Nutrition
- Biotechnology
