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Occurrence of bovine meat and milk factors (BMMF)and other circular ssDNA in food
Project
Project code: MRI-MBT-08-1040 BMMF
Contract period: 01.09.2020
- 31.08.2022
Purpose of research: Experimental development
Keywords: Microbiology, molecular biology, food safety
It has been postulated that the development of colon carcinomas and breast cancer is associated with the consumption of bovine meet- and milk products and that are therefore factors in these products which at least favour the development of the above-mentioned types of cancer. These factors are called bovine meat and milk factors (BMMF). In the meantime, a number of small circular single-stranded DNA molecules have been detected in bovine milk and serum and in brain of patients suffering from Multiple Sclerosis. These BMMF show high homologies to Transmissible Spongiform Encephalopathy (TSE-) associated circular DNA. Objectives of the project: 1. Detection of BMMF and similar circular ssDNA in milk and milk products (yoghurt/cheese) and beef (establishment of the detection method) 2. Studies on the occurrence of BMMF and other circular ssDNA in food of non-bovine origin 3. Investigations of infectivity, replication and expression of BMMF and other circular ssDNA in eukaryotic cells 4. Examinations regarding inactivation of BMMF and other circular ssDNA by food technology methods
Section overview
Subjects
- Food Processing
- Biotechnology
- Food microbiology
- Toxicology
Framework programme
Funding programme
Excutive institution
MRI - Department of Microbiology and Biotechnology (MRI-MBT)
