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MedVet-Staph
Project code
: 01KI1014A/F + 01KI1301A/H
Contract period
:
- 2016
The research network MedVet-Staph is focused on the occurrence, dissemination and biological characteristics of Staphylococcus aureus bacteria and methicillin-resistant S. aureus (MRSA) in particular which are transmittable from animals to humans or vice versa. MedVet-Staph is analyzing the virulence, pathogenicity, antimicrobial resistance and host-sell interaction of these bacteria as well as the mechanisms facilitating a transmission between humans and animals. Moreover, phylogenic changes of zoonotic S. aureus are assessed. Furthermore, the research network elucidates the consequences of a zoonotic S. aureus/MRSA reservoir on the health of humans and animals and the mechanisms enabling their dissemination among animals, in humans healthcare facilities and in the food chain.
Coordinating institution
Subprojects
Prospective studies on the epidemiology and burden of disease/colonization in humans and animals and novel antimicrobial resistance pheno- and genotypes
- Transferable antimicrobial resistance among MRSA and MSSA from humans and animals
- Assessment of MRSA-infected companion animals as a reservoir for MRSA in the community
- Übertragung von MRSA mit Herkunft bei Tieren auf Menschen auf der Grundlage von Populationsanalysen relevanter klonaler Linien und von prospektiven Studien
Molecula mechanisms of host-pathogen interaction, pathogeicity and virulence of S. aureus from humans and animals
Modelling of transmission, spread and risk assesment
- Interdisciplinary Research Network (MedVet-Staph) IP3 - MRSA in the food chain: Source attribution and transmission modelling based on molecularcharacterization of isolates from the food chain and from humans
- Epidemiological modeling of the spread of MRSA in pig farming; identification of risk factors for zoonotic infections and identification of control strategies
- LA-MRSA spread from food to consumers. 2nd funding phase
Cross-Sectional Activities
Epidemiology of human LA-MRSA infection and colonization
Strategies for intervention, therapy and diagnosis of LA-MRSA
Influences of ecological niches and host-adaptation on LA-MRSA
