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Gene Center Munich
Institution
Section overview
Description
The Gene Center of the University of Munich (LMU) conducts interdisciplinary research and teaching in key areas of the life sciences. The aim of our research is to unravel the molecular mechanisms underlying fundamental biological processes, with special emphasis on the regulation of gene expression. Disciplines represented include structural biochemistry, cell biology, genetics, developmental biology, and virology. Celebrating its 25th anniversary, the Gene Center continues to explore new frontiers. It is now expanding towards the emerging discipline of molecular systems biology, with the aim of developing mechanistic and quantitative descriptions of regulatory processes and networks.
Activities
- Research
Parent institution
Coordinated projects
- GRK 1029 P2: Generating new transgenic pig models for diabetes research
- GRK 1029 P4B: Investigation of the insulinotropic effect of Betacellulin in transgenic mice
- GRK 1029 P6: Proteome analysis of hepatocellular growth processes: studies on the model of GH-transgenic mice hepatopathy
- Integrative OMICS-profiles for the definition of new phenotypes with relevance for the characteristic complexes metabolism and reproductive performance at cattle and hog
- Nuclear architecture, epigenetic status of chromatin and DNA repair in mammalian IVF and NT preimplantation embryos studied on three dimensions by light optical nanoscopy and electron microscopy
- Oocyte maturation and developmental competence at different life cycle stages: structural, molecular and functional analyses in the bovine model
- Proteomic analysis of mastitis pathogen-induced signaling pathways
Work package leader of collaborative projects
Involved in research projects
- GRK 1029 P1C: Transcriptome analysis of the endometrium during the cycle and the embryo-maternal interaction at the beginning of the fixation of the conceptus in mares
- GRK 1029 P5: Studies on the molecular pathogenesis of glomerulosclerosis in transgenic mouse models
- Production of pigs with a genetic predisposition for pancreatic cancer
Contact
Gene Center Munich
Feodor-Lynen-Str. 25
81377 München
Bavaria
Germany
Phone: +49 89 2180- 76965
Fax: +49 89 2180- 76999
Email: menacher(@)genzentrum.lmu.de
